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Wednesday, January 30, 2008

Cell Therapies And Diabetes

Type 1 diabetes is caused by autoimmune destruction of pancreatic stem cells and is characterized by absolute insulin insufficiency. The monocellular nature of this disease and endocrine action of insulin make this disease an excellent candidate for cellular therapy. Furthermore, precedent for cellular therapies has been set by successful cadaveric whole pancreas and islet transplantation. In order to expand the supply of cells to meet current and future needs, several novel cell sources have been proposed, including human stem cells or islets expanded in culture, islet xenografts and pancreatic ductal progenitor cells. Surrogate stem cells derived from hepatocytes, intestinal K cells or non-endodermal cell types have also been suggested. Stem cells found in bone marrow and umbilical cord blood have been used extensively to repopulate the haematopoietic system and offer the possibility of autologous transplantation.

Recent studies have suggested that these stem cells may also have a broader capacity to differentiate, possibly into other cells.

Stem cells from embryonic sources, such as human embryonic stem and embryonic germ cells, have the ability to proliferate extensively in culture and have an inherent developmental plasticity that may make them a potentially unlimited source of cells that can sense glucose and produce mature insulin. The wide range of proposed cell sources and our increasingly clear picture of pancreatic development suggest that novel cellular therapies might one day compete with non-cellular glucose sensing and insulin delivery devices.

The current best medical practice for those with type 1 diabetes includes insulin by multiple daily injections or continuous pump infusion. Recently developed insulin analogues have helped to more closely approximate normal glucose homeostasis and have been especially beneficial in reducing hypoglycaemia while tightly controlling blood glucose. Glargine insulin provides nearly twenty four hours of low level basal insulin activity, while meal-time peaks in activity can be mimicked by administration of rapid acting insulin can be paused to avert hypoglycaemia.

Wayne Channon, Director of Cells4Life Ltd, a Stem cell and cord blood storage expert. Stem cell and cord blood storage.

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How Does Flaxseed Help Cure Skin Conditions?

People's desire for natural supplements has grown throughout the years. Natural supplements and natural therapies have become increasingly popular over the last couple of decades. Flaxseeds are among the most popular in the latest craze for natural supplements. In fact flaxseeds are set to help cure many conditions, including skin conditions.

What do Flaxseeds do to help keep us Healthy?

Flaxseeds contain several different substances that may be beneficial to a person's health. One of these substances is called alpha-linolenic acid. Alpha-linolenic acid is in a group that many people heard of called omega-3 fatty acids. Omega-3 fatty acids are among the fatty acids that are necessary for our nutrition.

Omega-3 fatty acids are generally found in foods like a fish, particularly in a fish called salmon. This makes it difficult for people that either don't like fish or don't eat salmon on a regular basis to gain a sufficient amount of omega-3 fatty acids in their diet.

Flaxseed also contains lignans which may have antioxidant effects. Although there are differing opinions on the matter, lignans may have a positive effect for people that have cancer, and possibly to even help prevent cancer.

Flaxseeds can be beneficial for skin conditions, because they have anti-inflammatory effects. This can help certain inflammatory skin conditions such as acne be reduced in severity. Also, due to its potential cancer fighting abilities, flaxseeds may also be beneficial for the skin condition skin cancer.

In fact, recent research has shown that people with skin conditions such as eczema and psoriasis have seen remarkable improvement when flaxseed was added the their diet over a period of time. Most skin conditions are exacerbated from a lack of LNAs in diets. People who consume flaxseeds on a steady basis have seen their skin get softer and smoother. Also, people with dry skin and dandruff have also seen a marked improvement too.

Other Benefits of Flaxseeds

In addition to being helpful for skin conditions, flaxseeds can be helpful for many other ailments. While scientists have not yet proven the ability of flaxseeds to help with particular diseases, it has been suggested they can help with things like heart disease, diabetes, all types of cancer, hemorrhoids, gout, and joint pain. Perhaps the most publicized potential benefits of flaxseeds are those against heart disease and cancer.

Studies have shown that flaxseed oil, in addition to ground flaxseeds, may actually reduce cholesterol. In addition to reducing cholesterol flaxseed oil may be beneficial in the fight against heart disease due to the fact that it reduces inflammatory responses by the body, thereby helping to prevent heart attacks. These inflammatory responses can cause circulatory problems and hardening of the arteries.

Flaxseeds are said to fight cancer due to the fact that the omega-3 fatty acids found within it act as antioxidants in the body. Antioxidants may be helpful in fighting nearly every type of cancer.

Kerry Ng is a successful Webmaster and publisher of The Omega3 Flaxseed Blog. Click here for more helpful information about Omega3 Flaxseeds: http://www.omega3flaxseeds.com/the-proven-benefits-of-flaxseed-and-lna

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